Yahoo! released new Flickr Uploadr v3.0 beta application which lets you bulk upload any number of images from you desktop to Flickr.
This application lets you select any number of photos, set privacy options and add description, tags, titles for these photos before uploading them.
Another cool feature of this application is you can prepare a new batch of photos while one batch of photos are being uploaded to flickr. This application is compatible with Windows as well as Mac operating systems. Here are the direct download links of Windows and Mac applications